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photonamic

The name photonamic consists of photo (= light) and dynamics and thus represents the field of activity of photonamic GmbH & Co. KG ("photonamic"). The effect of light on certain molecules is manifold and ultimately leads not only to coloration, but can also lead to fluorescence or initiation of chemical reactions.
Photonamic takes advantage of these dynamics of light by using a specific molecule that is metabolized into a photosensitizer in cells or in cell assemblies or in the body. Depending on the choice of wavelength, this can lead to a wide variety of effects triggered by the light. The use of light and the application of photosensitizers is not really a new principle, but has been known and researched for decades.
photonamic has set itself the goal of researching and developing these possibilities in a targeted manner in order to derive diverse applications from them. Unlike many other approaches, the molecule primarily used by photonamic is a precursor of the actual photosensitizer, which is metabolically converted into the light-excitable molecule and exhibits the corresponding photodyna-mic properties. The resulting fascinating applications in imaging and also therapy form the core of photonamic's activities.
Through numerous collaborations and projects with partner companies, academic institutions for clinical applicability and also with corresponding equipment companies for light sources, sensors and camera systems, the diversity of these technologies can be imagined.

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Phase 3 Study of 5-ALA in Meningioma Surgery Meets Primary Endpoint

Pinneberg, Germany, April 23rd 2025. photonamic GmbH & Co KG (Photonamic) are pleased to announce that our U.S. subsidiary, NX Development Corporation (NXDC), has successfully completed its phase 3 study (MEN-301) and comfortably met the primary endpoint, investigating 5-ALA as an adjunct in meningioma patients undergoing fluorescence-guided surgery. Meningiomas are the most common type of primary brain tumor. Under the trade names Gleolan® in the United States and Gliolan® in Europe, 5-ALA has primarily been used in the approved indication of fluorescence-guided resections of malignant gliomas (WHO grade III and IV) in combination with a surgical microscope and blue light source. Meanwhile, experience has demonstrated that meningiomas may also show fluorescence. This was the motivation leading to the initiation of the MEN-301 study, conducted primarily at centers in the United States, as well as centers in Germany and Austria.

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"Marketing Authorization for Gliolan® granted in Jordan"....more

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